Here are the clues

1) Hello Again- Use the Internet
2) Playtastic- You found the Play button
3) Crossroads- Discovered the Main Menu
4) Mission Accepted- Start the game
5) Tiles Loaded- Loaded the level
6) Home Sweet Home- Found your home
7) First Floor- Reach the first floor
8) Second Floor- Reach the second floor
9) Third Floor- Reach the third floor
10) Fourth Floor- Get to the fourth floor
11) Fifth Floor- Get to the fifth floor
12) Cataclysm- Welcome to reality
13) Storefront- Found the store
14) Thrifty- Found the second shop room
15) Windowshopper- Found the third shop room
16) Shopper- Found the fourth shop room
17) Big Spender- Found the fifth shop room
18) Shopaholic- Found all the shop rooms
19) Navigationer- Found all the areas
20) Just Gave In- Bought the first level pack
21) Add-on-tastic- Bought the second level pack
22) Deluxe Edition- Bought the third level pack
23) Gold Edition- Bought the fourth level pack
24) Platinum Edition- Bought the fifth level pa
25) Charge It!- Buy all the level packs
26) Wallet Burn- Press a purchase button
27) No Refunds- Jump on a purchased upgrade
28) Panicked Shopper- Panic in the shop
29) Home Emergency- Panic at home
30) Panic Attack- Panic Ten Times
31) Thirsty- Drink some water
32) Save the Whales- Drink All the water
33) Wheel And Deal- Jump on the hamster wheel
34) Full Speed Ahead- Reach full speed on wheel
35) Two Trick Pony- Run both ways on the treadmill
36) One...- Go once over the wheel
37) Two...- Go twice over the wheel
38) Three...- Go three times over the wheel
39) Four...- Go four times over the wheel
40) Five!- Go five times over the wheel
41) Dismount- Jump off the wheel
42) Teleport!- Go through a teleporter
43) Beam Me Up- Exit and enter every teleporter
44) Free Fall Forever- Get in a downward vertical loop
45) Falling Up- Create an infinite teleport loop upwards
46) Corpse Loop- Get a corpse in an infinite loop
47) Reenter- Enter the same teleporter twice
48) You Might As Well- Jump up and down
49) Bouncy- Jump ten times
50) Flouncy- Jump fifty times
51) Trouncy- Jump one-hundred times
52) Pouncy- Jump two-hundred fifty times
53) Full Jump- Do a big jump
54) No Double Jumping- Try to double jump
55) See Ya- Die.
56) Subtle Movement- Move a tiny amount across the screen
57) Panic Attack- Hit the panic button
58) Midflight Deceased- Die while airborne
59) MultiDeath- Die ten times
60) MegaDeath- Die fifty times
61) GigaDeath- Die one hundred times
62) Impaler- Die on spikes
63) Stalagmite- Die on upward spikes
64) Stalacite- Die on downward spikes
65) Staleftmite- Die on leftward spikes
66) Straightcite- Die on rightward spikes
67) I Love You Spike- Die ten times on the same spike
68) Pink- Turn a spike pink
69) First Floor Pink- Turn first floor spikes pink
70) Second Floor Pink- Turn second floor spikes pink
71) Third Floor Pink- Turn third floor spikes pink
72) Fourth Floor Pink- Turn fourth floor spikes pink
73) Fifth Floor Pink- Turn fifth floor spikes pink
74) Pinky Swear- Turn half the spikes pink
75) Pinky Promise- Turn all the spikes pink
76) WASD- Prefer the WASD control
77) Arrow Keys- Prefer the Arrow control
78) Colour My Tile- Paint a block
79) 100 Pretty Tiles- Colour one-hundred tiles in one room
80) First Floor Painted- Paint one-hundred tiles on the first floor
81) Second Floor Painted- Paint one-hundred tiles on the second floor
82) Third Floor Painted- Paint one-hundred tiles on the third floor
83) Fourth Floor Painted- Paint one-hundred tiles on the fourth floor
84) Fifth Floor Painted- Paint one-hundred tiles on the Fifth floor
85) Coloured 50- Paint fifty tiles
86) Coloured 100- Paint one- hundred tiles
87) Coloured 150- Paint one- hundred fifty tiles
88) Coloured 250- Paint two- hundred fifty tiles
89) Coloured 500- Paint five- hundred tiles
90) Launcher- Touch A Launcher
91) Launcher Cleaner- Clean all the first floor launchers
92) Launcher Scrubber- Clean all the second floor launchers
93) Launcher Polisher- Clean all the third floor launchers
94) Launcher Rinser- Clean all the fourth floor launchers
95) Launcher Washer- Clean all the fifth floor launchers
96) Launcher Powerwasher- Clean all launchers
97) Look, a Penny- Find a coin
98) Penny bags- Collect thirty coins
99) Moneymaker- Collect sixty coins
100) Pennywise- Collect ninety coins
101) It Prints Money- Collect one- hundred twenty coins
102) Scrooge- Collect one- hundred forty coins
103) 1st Collection- Collect first floor coins
104) 2nd Collection- Collect second floor coins
105) 3rd Collection- Collect third floor coins
106) 4th Collection- Collect fourth floor coins
107) 5th Collection- Collect fifth floor coins
108) Gotta Collect 'em All- Collect all the coins
109) I'm Glad You're Here- Stick around for ten seconds
110) Good Company- Stick around for thirty seconds
111) BFFs- Stick around for sixty seconds
112) West Side- Look West
113) East Side- Look East
114) Dizzy- Flip direction five times in a second
115) Hover- Stay Airborne for six seconds
116) Dead Crowd- Generate three corpses at once
117) Corpsaholic- Generate five corpses at once
118) Necrophilia- Generate ten corpses at once
119) Spike Corpse Hoedown- Land three corpses together on the same spike
120) Corpse Levitation- Suspend a corpse for two seconds
121) Corpse Juggling- Suspend 5 different corpses
122) Body Drop- Send a corpse to another floor
123) Undead Touch- Touch a dead corpse
124) Telecorpse- Teleport a corpse
125) Teletired- Teleport 50 times
126) Relapse- Panic while touching a checkpoint
127) Respawnorama- Respawn at every checkpoint
128) Clicky- Click click clickaroo
129) Not Left Click- Check out the Right Click Menu
130) BILLY MAYS- Enable Caps Lock
131) Scrolly- Scroll the achievements list
132) Extreme Scrolling- Scroll to the very bottom
133) So Happy!- Make a happy face with keyboard letters
134) Erasure- Push the backspace key
135) Quality Time- Set the quality lower
136) Waltzing Ma- Push the tilda key (~)
137) Partial Colon- Push the semicolon
138) Silence is Golden- Push the mute button
139) Same combo as my luggage!- Push 1,2,3,4,5
140) Paste in Notepad- Click the centre of the wheel
141) Dash!- Run 20 metres in-game
142) Look I'm Big!- I made music!
143) Keyboard Hero- Hit every piano key
144) Ode to Joy- Play Ode to Joy on the Piano (E E F G G F E D)
145) Twinkle Twinkle- Play Twinkle Twinkle (Little Star) on the Piano (C C G G A A G)
146) Row Row Row Your Boat- Play Row your Boat on the Piano (C C C D E E D E F G)
147) Piano Slide Up- Hit every piano key from bottom to top
148) Piano Slide Down- Hit every piano key from top to bottom
149) Corpse Organ- Land a corpse on a piano key
150) Chord- Play a note while your corpse plays another
151) Harmony- Play a note while 2 corpses play another
152) High and Low Cs- Jump from the last key to first
153) Fort Alpha- Find Hidey Hole 1
154) Fort Beta- Find Hidey Hole 2
155) Fort Gamma- Find Hidey Hole 3
156) Fort Delta- Find Hidey Hole 4
157) Fort Zeta- Find Hidey Hole 5
158) Fort Eta- Find Hidey Hole 6
159) Fort Theta- Find Hidey Hole 7
160) Fort Iota- Find Hidey Hole 8
161) Fort Kappa- Find Hidey Hole 9
162) Fort Lambda- Find Hidey Hole 10
163) Fortable- Find a Hidey Hole
164) Oooooooh *Push*- Push the orange button.
165) No button!- Release the orange button.
166) Pressing Issue- Push the orange button 20 times.
167) And.... hold!- Hold the orange button down for 3 seconds
168) Pretty Button!!!- Look at the button
169) Quick to Strike- Hit the orange button twice in a second
170) Inactivity- Don't do anything for ten seconds
171) Survival- Don't die for 20 seconds
172) Invulnerable- Don't die for 40 seconds
173) One Wheel!- Stop one slot reel
174) Two Wheel!- Stop two slot reels
175) Three Wheel!- Stop all the reels
176) Insert Coin- Start the reels
177) RGB- Stop the reels on Elephant, Llama, Giraffe
178) Elephant Jackpot!- Get all Elephants in the slot machine
179) Emu Jackpot!- Get all Emus in the slot machine
180) Llama Jackpot!- Each all Llamas in the slot machine
181) Consolation Prize- Match 2 random symbols in the slot
182) Not a Winner- Match no symbols in the slots
183) Trip Giraffes- Match 3 giraffes on the slots
184) Addicted Gambler- Lock the slots 30 times
185) Left it Running- Leave the floor while the slot wheels are running
186) Reely Restart- Restart a reel
187) Reel it backwards- Hit the reels in the reverse order
188) Three Times the Minute- System clock time is divisible by 3
189) Rollout!- Roll the mouse off the screen
190) Mouseing Around- Move the cursor 1 foot across the screen
191) 10 Foot Mousetrek- Move the cursor 10 feet across the screen
192) EleClick- Hey, that tickles!
193) Won't Follow Directions- You just had to do it...
194) Further Fall- Fall two floors
195) Super Fall- Fall three floors
196) Mega Fall- Fall four floors
197) Colossal Fall- Fall all the way to the bottom from the top
198) Further Ascend- Rise two floors
199) Super Ascend- Rise three floors
200) Mega Ascend- Rise four floors
201) Colossal Ascend- Rise from the bottom to the top
202) I Can't Live With This- Die outside
203) Safer Inside- Go back inside from the Cataclysm
204) Two Browser Windows- Open two browser windows of the same game
205) Break Time!- Find the hot coffee feature
206) Break Off!- Start playing again on the main screen
207) Buzz- Move around in the coffee feature
208) The Burn!- Jump in the hot coffee mug
209) Warm...- Fall below the hot coffee stage
210) Colder...- Fall further below the coffee stage
211) Even Colder...- Fall even further below the coffee stage
212) Cold Coffee!- Find the secret secret stage
213) The Final Straw- Stand on top of the straw
214) There's the pump!- Start the pump
215) Begin the fill!- Fill the first floor height
216) Keep Filling Captain!- Fill the second floor height
217) The Pressure!- Fill the third floor height
218) The Bends!- Fill the fourth floor height
219) Full Glass!- Fill the entire building with water
220) Draining- Drain the entire building from the fifth floor
221) Hey, a Pastry!- Poop a Pastry
222) Yum Yum!- Eat a Pastry
223) Maximum Pastry!- Poop 10 pastries
224) Pastry Chef- Poop 30 pastries
225) Pastry Connoisseur- Consume 25 pastries
226) Bloataphant- Eat 50 pastries
227) Doggy Bag- Launch a pastry into a teleporter
228) To Go Order- Use a launcher to launch a pastry
229) Pastry for the Dead- Give a pastry to a corpse
230) Soggy pastries- Make pastries underwater
231) Drown- Die underwater
232) Do a Barrel Roll!- Push Z or R twice!
233) I Don't Get It- Access the walkthrough
234) Stop and Hop- Jump without moving left or right
235) Aww Poor Puppy- Look hopeless
236) A Decade- Earn 10% of the achievements
237) It's Roaring!- Earn 20% of the achievements
238) Days Past September- Earn 30% of the achievements
239) By Volume- Earn 40% of the achievements
240) Fifty- Earn 50% of the achievements
241) Every Time- Earn 60% of the achievements
242) Hey, Youre Passing!- Earn 70% of the achievements
243) B Average- Earn 80% of the achievements
244) Final Run- Earn 90% of the achievements
245) Almost There!- Earn 95% of the achievements
246) I Can't Shake Him!- Earn 96% of the achievements
247) Almost... there...- Earn 97% of the achievements
248) Stay on Target!- Earn 98% of the achievements
249) Pull Up!- Earn 99% of the achievements
250) Absolute Completion- Earn every other achievement

I hope you'll figure out how to beat Achievement Unlocked 2. :P